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Benazepril br The change in tumour volume was also observed
2021-03-03
The change in tumour volume was also observed and results re-vealed that the tumour growth was inhibited in the mice receiving the EGCG formulations (Fig. 9). The percent increase in tumour volume in mice treated with EGCG-SLN and EB-SLN was 3.78% and 0.78%, re-spectively, as compared to mice rece
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br Discussion br In most countries
2021-03-03
Discussion In most countries, the standard adjuvant treatment for patients with HER2+ eBC is chemotherapy combined with one year of trastuzumab, which showed a significant benefit in terms of disease-free survival (DFS) and OS.4 On one hand, a high percentage of these patients will still experi
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br In vivo anti http www glpbio com simage
2021-03-03
2.9. In vivo anticancer efficiency Based on efficient accumulation of nanocomposites in tumor region and the attractive synergistic treatment effect for induce MCF-7/ADR cell death. And then in vivo PTT/PDT/chemo-therapy combination therapy experiments were performed by using BPNs-PDA-PEG
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br Mechanism by which BPS induced DNA methylation may simila
2021-03-03
Mechanism by which BPS induced DNA methylation may similar to other environmental chemicals. The mechanism of environ-mental chemicals induced changes in global DNA methylation status may rely on two often described hypotheses. First, evidence has demonstrated the direct action of environmental ch
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br Independent variables levels br Dependent variables br
2021-03-03
Independent variables levels Dependent variables I II Lipid/drug ratio (w/w) 5 10 Particle size (nm) Aqueous to organic phase volume ratio 5 10 Polydispersity index Surfactant concentration (%) 0.5 1 Encapsulation efficiency Release efficiency (%) S. Taymouri et al.
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br Recently increasing attention has been paid to the
2020-08-30
Recently, increasing attention has been paid to the presence of specific and strongly over-expressed receptors, notably the epidermal growth factor receptor (EGFR), on the surface of cells of many cancer types including NSCLC [7]. The EGFR plays a key role in signalling Corresponding authors.
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br QUANTIFICATION AND STATISTICAL ANALYSIS br Data are prese
2020-08-30
QUANTIFICATION AND STATISTICAL ANALYSIS Data are presented as mean ± SEM, as indicated in the legend of each figure. The significance of the differences between groups was evaluated using unpaired t test, p value < 0.05 was considered significant. Statistical parameters including the precision
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br Given that CD plays a pivotal role in regulating
2020-08-30
Given that CD133 plays a pivotal role in regulating cancer metas-tasis and therapeutic resistance and that both of cancer metastasis and drug resistance are the major contributors to cancer death, targeting CD133 in cancer patients who have metastatic disease would be the best strategy to bring do
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br In addition as well as
2020-08-28
In addition, as well as for membrane potential, there is a differential effect of the co-culture with different fibroblast 1428935-60-7 for ROS. The co-culture with the AF produces a greater increase of ROS in the tumor cells than the co-culture with CF1. On the contrary, the increase of ROS in both
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br B br C br ShamSham
2020-08-28
B C ShamSham ShamBCF1BCF2BCF3 3000 Blood exosome Sham BCF Sham BCF Sham BCF D TCGA Overallsurvival Time (Months) E Primary Brain- Other- No- Brain- met met met met I HBMEC Control J Sham Numberoftubes/field G Intracellular Exosom
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Rottlerin br J Kremer K Steenstrup Pedersen C Igel Active
2020-08-18
[18] J. Kremer, K. Steenstrup Pedersen, C. Igel, Active Learning With Support Vec-tor Machines, 4, Wiley Interdisciplinary Reviews: Data Mining and Knowledge Discovery, 2014, pp. 313–326. [21] H. Samet, Foundations of Multidimensional and Metric Data Structures, Else-vier, Amsterdam, 2006. [
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b iframe width height src https www youtube
2020-08-18
r> METHOD DETAILS Tissue quality control via RNA integrity measurement After homogenization in a MM301 mechanical homogenizer (Retsch, Germany) using a metal ball for 2 3 2 min at 25 s-1 in 600 mL of RLT buffer (QIAGEN, Germany) with 1% b-mercaptoethanol, total RNA was isolated using RNeasy M
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Giralt M Villarroya F Mitochondrial uncoupling
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Giralt, M., Villarroya, F., 2017. Mitochondrial uncoupling and the regulation of glucose homeostasis. Curr. Diabetes Rev. 13, 386–394. Grippo, P., Maker, A.V., 2017. Targeting cancer with tumor-specific therapeutic strate-gies-metabolic reprogramming beyond the Warburg effect. Transl. Cancer Res. 6,
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br Av treatment increases primary tumor volume
2020-08-18
3.2.1. Av treatment increases primary tumor volume and does not block metastasis in the xenograft mouse model Av treatment increased the volume of primary tumors of NSG mice xenografted with MDA-MB-231 115144-35-9 (Supplementary Fig. S1). Moreover, Av treatment failed to inhibit metastases of M
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br GSH NADH and NADPH Measurements
2020-08-18
GSH, NADH and NADPH Measurements Free Heme Measurements Free heme was extracted with neutral acetone as described (Espinas et al., 2012). Heme from neutral acetone extracts was quantified with the Heme assay kit (MAK316-1KT, Sigma-Aldrich), and measurements were normalized to protein concent